Qijian Bio-Pharmaceutical Co., Ltd.

Monosialotetrahexosylganglioside Sodium (GM-1) 

CAS:  37758-47-7

Structure chart:

Molecular formula:C₇₃H₁₃₀N₃NaO₃₁ or  C₇₅H₁₃₄N₃NaO₃₁

Formula weight:    1568.84  or  1597.18

Category:White or off-white Powder or liquid

Brand:Satis-key ®

Feature: environmental protection, safe, higher yield

Indication:

Neural Repair

Hypoxic ischemic encephalopathy

Traumatic and various cardiovascular diseases of nerve damage

A variety of chronic diseases in the late nerve dysfunction (e.g. the numbness of late diabetes)

Brain atrophy

Alzheimer's disease

Mental disorders

Parkinson's disease

Packaging and specifications:

Ampoule bottle

2ml:20mg

2ml:40mg

5ml:100mg

Or in aluminum foilbag, 1kg/bag

Storage: Sealed preservation, avoid sunlight 

Exp.: 24 months

Standard:

China National Standard

1.A description of Monosialotetrahexosylganglioside Sodium

Ganglioside is sheath glycolipids, which containing sialic acid is the most abundant in the nervous system

According to the different content of sialic acid, divided into GM (Single saliva),GD( two saliva),GT(three saliva) etc.

According to the different number of glycosyl ,divided into GM1(4 glycosyls)、GM2(3 glycosyls )、GM3(2 glycosyls )

In exogenous ganglioside, only GM1 participates in neural development, neural axon growth, signal transduction and other functions through the blood-brain barrier (BBB).

2. GM1 mechanism of action

(1) To protect cell membrane : Ganglioside is natural component of nerve cell membrane , which can adjust protein in cell membrane, stable and strength double layer structure of bilayer lipid membrane.

(2) Regulation of ion channels : To maintain the Na+-K